Antioxidant BHT 264
CAS:128-37-0
Purity:99%
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Product Details
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Uses |
γ-Glutamyl donor substrate used in spectrophotometric determination of transglutaminase (TGase) activity. Z-Gln-Gly was used to enzymatically synthesize N-linked neoglycoproteins. |
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Biochem/physiol Actions |
N-Benzyloxycarbonyl-L-Glutaminylglycine (Z-Gln-Gly, Z-QG) is used as a substrate to differentiate and characterize transglutaminase(s) (TGase) that catalyzes the post-translational covalent cross-linking of Gln- and Lys-containing peptides. Z-QG supports glutamyl-level cross-linking applications thruough surface modification. |
InChI:InChI=1/C15H19N3O6/c16-12(19)7-6-11(14(22)17-8-13(20)21)18-15(23)24-9-10-4-2-1-3-5-10/h1-5,11H,6-9H2,(H2,16,19)(H,17,22)(H,18,23)(H,20,21)
Several series of dipeptides and tripept...
Cbz-L-Gln
α-N-carbobenzyloxy-L-glutamine-glycine
| Conditions | Yield |
|---|---|
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Multi-step reaction with 2 steps
1: Et3N; DMAP / acetonitrile / 0.75 h / 20 °C
2: Et3N / acetonitrile; H2O / 1.67 h / 20 °C
With
dmap; triethylamine;
In
water; acetonitrile;
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Multi-step reaction with 2 steps
1: PCl3; pyridine
2: acetone; aqueous NaOH
With
pyridine; sodium hydroxide; acetone; phosphorus trichloride;
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Multi-step reaction with 2 steps
1: DCC, Et3N
2: aq. NaOH, Py
With
pyridine; sodium hydroxide; triethylamine; dicyclohexyl-carbodiimide;
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Multi-step reaction with 2 steps
1: (i) ClCO2Et, Et3N, THF, DMF, (ii) /BRN= 741933/
2: aq. NaOH / dioxane
With
sodium hydroxide;
In
1,4-dioxane;
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Z-Gln-Gly-OEt
α-N-carbobenzyloxy-L-glutamine-glycine
| Conditions | Yield |
|---|---|
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With
sodium hydroxide; acetone;
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With
sodium hydroxide;
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With
sodium hydroxide;
In
1,4-dioxane;
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With
pyridine; sodium hydroxide;
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Z-Gln-Gly-OEt
N-(O-ethyl-N-benzyloxycarbonyl-L-α-glutamyl)-glycine
N2-benzyloxycarbonyl-L-glutamine-(4-nitro-phenyl ester)
glycine
Cbz-L-Gln-Gly-Gly
[4-(3-amino-2-hydroxy-propylcarbamoyl)-2-benzyloxycarbonylamino-butyrylamino]-acetic acid
Z-α-L-Glutamyl-(γ-hydrazid)-glycin
