Your Location:Home >Products >5654-97-7

5654-97-7

  • Product Name:1,3-Dihydro-2H-pyrrolo[2,3-b]pyridin-2-one
  • Molecular Formula:C7H6 N2 O
  • Purity:99%
  • Molecular Weight:134.137
Get the best price

Product Details

  • CasNo: 5654-97-7
  • Molecular Formula: C7H6 N2 O
  • factory cost Chinese Manufacturer Supply 1,3-Dihydro-2H-pyrrolo[2,3-b]pyridin-2-one 5654-97-7 Competitive Price

    • Molecular Formula:C7H6 N2 O
    • Molecular Weight:134.137
    • Vapor Pressure:0mmHg at 25°C 
    • Melting Point:175 °C 
    • Refractive Index:1.594 
    • Boiling Point:362.474 °C at 760 mmHg 
    • PKA:3.42±0.20(Predicted) 
    • Flash Point:173.019 °C 
    • PSA:41.99000 
    • Density:1.286 g/cm3 
    • LogP:0.71420 

    1,3-DIHYDRO-2H-PYRROLO[2,3-B]PYRIDINE-2-ONE(Cas 5654-97-7) Usage

    Uses

    1,3-DIHYDRO-2H-PYRROLO[2,3-B]PYRIDINE-2-ONE is used for preparation of 3-(anilinomethylene)oxindoles and analogs as protein tyrosine kinase and protein serine/threonine kinase inhibitors.

    InChI:InChI=1/C7H6N2O/c10-6-4-5-2-1-3-8-7(5)9-6/h1-3H,4H2,(H,8,9,10)

    5654-97-7 Relevant articles

    Ambipolar organic field-effect transistors based on N-Unsubstituted thienoisoindigo derivatives

    Ashizawa, Minoru,Hasegawa, Tsukasa,Hikima, Takaaki,Kawamoto, Tadashi,Kohara, Akihiro,Masunaga, Hiroyasu,Matsumoto, Hidetoshi,Mori, Takehiko,Ohta, Noboru,Sugiyama, Haruki,Uekusa, Hidehiro,Yoo, Dongho

    , (2020/04/27)

    To investigate a hybrid of isoindigo and...

    Molybdenum hexacarbonyl mediated synthesis of indolin-2-one & azaindolin-2-one under catalyst free conditions

    Patil, Vikas S.,Pal, Shyam S.,Pathare, Ramdas S.,Reddy,Pathak, Arunendra

    supporting information, p. 6370 - 6372 (2015/11/16)

    Syntheses of indolin-2-ones and azaindol...

    7,7′-Diazaindirubin - A small molecule inhibitor of casein kinase 2 in vitro and in cells

    Cheng, Xinlai,Merz, Karl-Heinz,Vatter, Sandra,Christ, Jochen,W?lfl, Stefan,Eisenbrand, Gerhard

    , p. 247 - 255 (2014/01/17)

    Aza- and diaza-bisindoles were synthesiz...

    Exploring the Anticancer Activity of Functionalized Isoindigos: Synthesis, Drug-like Potential, Mode of Action and Effect on Tumor-Induced Xenografts

    Wee, Xi Kai,Yang, Tianming,Go, Mei Lin

    experimental part, p. 777 - 791 (2012/07/17)

    Meisoindigo has been used as an indirubi...

    5654-97-7 Process route

    3-(2-trimetylacetylamino)pyridylacetic acid
    1071087-00-7

    3-(2-trimetylacetylamino)pyridylacetic acid

    7-azaoxindole
    5654-97-7

    7-azaoxindole

    2-amino-3-pyridylacetic acid
    101860-97-3

    2-amino-3-pyridylacetic acid

    Conditions
    Conditions Yield
    With hydrogenchloride; Reflux;
    38%
    31%
    3,3-Dibromo-1,3-dihydro-2H-pyrrolo[2,3-b]-pyridin-2-one
    113423-51-1

    3,3-Dibromo-1,3-dihydro-2H-pyrrolo[2,3-b]-pyridin-2-one

    7-azaoxindole
    5654-97-7

    7-azaoxindole

    Conditions
    Conditions Yield
    With acetic acid; zinc; In acetonitrile;
    91%
    With acetic acid; zinc; In acetonitrile;
    91%
    With acetic acid; zinc; In acetonitrile; at 20 ℃; for 2h;
    91%
    3,3-Dibromo-1,3-dihydro-2H-pyrrolo[2,3-b]-pyridin-2-one; With formic acid; 5%-palladium/activated carbon; In methanol; for 12h; Reflux; Inert atmosphere;
    With potassium carbonate; In water; pH=8 - 9; Saturated solution;
    76%
    With hydrogen; palladium on activated charcoal; In ethanol; under 1551.4 Torr;
    75%
    With hydrogen; palladium on activated charcoal; In ethanol; under 1551.4 Torr; a convenient method for preparation of 7-azaoxindole. (The method is applicable to indole and substituted indoles.);
    75%
    With ammonium chloride; zinc; In tetrahydrofuran; water; at 20 ℃; for 2h;
    70%
    3,3-Dibromo-1,3-dihydro-2H-pyrrolo[2,3-b]-pyridin-2-one; With acetic acid; zinc; at 20 ℃; for 0.5h; Inert atmosphere;
    With sodium hydrogencarbonate; In water; ethyl acetate;
    With acetic acid; zinc;

    5654-97-7 Upstream products

    • 101860-97-3
      101860-97-3

      2-amino-3-pyridylacetic acid

    • 121-69-7
      121-69-7

      N,N-dimethyl-aniline

    • 438210-61-8
      438210-61-8

      1-(2-amino-[3]pyridyl)-2-diazo-ethanone

    • 113423-51-1
      113423-51-1

      3,3-Dibromo-1,3-dihydro-2H-pyrrolo[2,3-b]-pyridin-2-one

    5654-97-7 Downstream products

    • 126807-18-9
      126807-18-9

      1H-pyrrolo[2,3-b]pyridine-2,3-dione-3-oxime

    • 109535-73-1
      109535-73-1

      1,3-dihydro-3,3-dimethyl-2H-pyrrolo<2,3-b>pyridin-2-one

    • 5654-95-5
      5654-95-5

      1H-pyrrolo[2,3-b]pyridine-2,3-dione

    • 295327-24-1
      295327-24-1

      4-{[(2-Oxo-1,2-dihydro-3H-pyrrolo[2,3-b]pyridin-3-ylidene)methyl]amino}benzenesulfonamide

    Antioxidant BHT 264

    CAS:128-37-0

    Purity:99%

    Contact Now

    We will contact you as soon as possible


    提交